Targeted treatment of refractory primitive neuroectodermal tumor arising from an immature teratoma with crizotinib leading to a sustained response

oleh: Benjamin M. Snyder, Alex H. Lion, Amy E. Helvie, Mark S. Marshall, Michael J. Ferguson

Format: Article
Diterbitkan: Wiley 2023-01-01

Deskripsi

Abstract Here we present a case of metastatic PNET which arose from an immature teratoma that was refractory to standard Ewing sarcoma chemotherapy. This PNET was determined to have elevated levels of ALK protein via IHC. The patient was treated with crizotinib on a palliative basis with a sustained response.