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Background: There are significant issues in the treatment of cancer patients. Despite these issues, there is still room to explore unique lived experiences after survival. Aim: This study aimed to explore the experiences of cancer survivors after chemotherapy. Method: A descriptive phenomenological study was conducted in Zabol, Iran. A purposeful sample of 15 cancer survivors was selected to gather data using semistructured interviews. Colaizzi’s method was used for data analysis. Results: Four themes were extracted from the interviews. These were altered body image, mood swings, uncertain and dark future, and choosing a solitary lifestyle. Conclusion: Cancer patients experience various physical, psychological, and social changes including stress, anger, nervousness, despair, worthlessness, depression, social isolation, and even the wish to die after chemotherapy.