Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
oleh: Mairi M. Littleson, Christopher M. Baker, Anne J. Dalençon, Elizabeth C. Frye, Craig Jamieson, Alan R. Kennedy, Kenneth B. Ling, Matthew M. McLachlan, Mark G. Montgomery, Claire J. Russell, Allan J. B. Watson
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-03-01 |
Deskripsi
Development of comprehensive structure–activity relationships for coronatine has been a major goal in the agrochemical industry. Here, the authors report the gram-scale production and structure–activity relationship of parent coronafacic acid and ultimately rationalise the biological activity of analogues of this phytotoxin.