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Purpose: To report a rare case of endogenous endophthalmitis caused by Staphylococcus capitis. Observation: A 34-year-old male patient with a history of gonococcal urethritis and arthritis presented with right endogenous endophthalmitis. Vitreous biopsy culture confirmed Staphylococcus capitis involvement. The patient was treated with pars plana vitrectomy, intravitreal vancomycin, and ceftazidime injections and systemic antibiotics. Conclusion and importance: Staphylococcus capitis-related endogenous endophthalmitis has rarely been reported in the literature. None of the published reports specifically describe its clinical course and management.