Red light-induced conjugation of amines through amide bond formation triggered via photooxidation of 3-acylindolizines
oleh: Kenji Watanabe, Asuka Kuratsu, Daisuke Hashizume, Takashi Niwa, Takamitsu Hosoya
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-08-01 |
Deskripsi
Photoinduced conjugation has been broadly used for functionalization of molecules but is limited by possible photodegradation. Here, the authors report a robust amide bond formation method based on the photoreaction of 3-acylindolizines with amines triggered via red-light irradiation in nearly quantitative yields within less than 5 min.