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In order to evaluate resistance of Phalaris minor biotypes, sampled from wheat fields of Fars and Golestan provinces, to ACCase inhibiting herbicides, a dose-response study was conducted under controlled conditions in greenhouse of Ferdwosi University of Mashhad. The results indicated that AR, SR3, MR4, FR2, FR4, and FR8 populations of Fars and GR2-1 biotype from Golestan have been resistant to diclofop-methlyl. Different levels of resistance maybe are because of involving different mechanisms in studied populations. AR, SR3, and MR4 showed a cross-resistance to the applied herbicides. These biotypes indicated a 5- to 11-fold and a 7- to 8-fold increase in resistance to diclofop-methlyl and clodinafop-propargyl, respectively compared with the susceptible biotype. Among these biotypes, SR3 showed the highest resistance to both herbicides. Key words: Phalaris minor, herbicide resistance and ACCase inhibitor.