Briarenols Q–T: Briaranes from A Cultured Octocoral <i>Briareum stechei</i> (Kükenthal, 1908)
oleh: Yi-Lin Zhang, Chih-Chao Chiang, Yi-Ting Lee, Zhi-Hong Wen, Yang-Chang Wu, Yu-Jen Wu, Tsong-Long Hwang, Tung-Ying Wu, Chia-Yuan Chang, Ping-Jyun Sung
| Format: | Article |
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| Diterbitkan: | MDPI AG 2020-07-01 |
Deskripsi
Our continuous chemical study of a cultured octocoral <i>Briareum stechei</i> led to the isolation of four new briarane diterpenoids, briarenols Q–T (<b>1</b>–<b>4</b>). The structures of new metabolites <b>1</b>–<b>4</b> were established by spectroscopic methods, and compounds <b>3</b> and <b>4</b> were found to inhibit the generation of inducible nitric oxide synthase (iNOS) from RAW 264.7 stimulated by lipopolysaccharides (LPS).