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The review covers automatic segmentation of images by means of deep learning approaches in the area of medical imaging. Current developments in machine learning, particularly related to deep learning, are proving instrumental in identification, and quantification of patterns in the medical images. The pivotal point of these advancements is the essential capability of the deep learning approaches to obtain hierarchical feature representations directly from the images, which in turn is eliminating the need for handcrafted features. Deep learning is expeditiously turning into the state-of-the-art for medical image processing and has resulted in performance improvements in diverse clinical applications. In this review, the basics of deep learning methods are discussed along with an overview of successful implementations involving image segmentation for different medical applications. Finally, some research issues are highlighted and the future need for further improvements is pointed out. Keywords: Image segmentation, Deep learning, Machine learning, Biomedical images