Differential ion mobility mass spectrometry in immunopeptidomics identifies neoantigens carrying colorectal cancer driver mutations
oleh: Yuriko Minegishi, Kazuma Kiyotani, Kensaku Nemoto, Yoshikage Inoue, Yoshimi Haga, Risa Fujii, Naomi Saichi, Satoshi Nagayama, Koji Ueda
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-08-01 |
Deskripsi
An optimized method for mass spectrometry based immunopeptidomics analysis using high-field asymmetric waveform ion mobility spectrometry is presented and identifies 44,815 HLA-bound peptides (HLAp) from colorectal cancer samples.