High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates
oleh: Salman Sohrabi, Danielle E. Mor, Rachel Kaletsky, William Keyes, Coleen T. Murphy
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
Salman Sohrabi et al. develop an automated, high-throughput assay to study spasm-like curling behavior in C. elegans, which is related to motor control symptoms in Parkinson’s disease. They apply this screening approach to identify four candidate drugs for potential late-in-life interventions for Parkinson’s disease.