Generation of a human induced pluripotent stem cell line (SHUPLi002-A) from PBMCs of a healthy female donor

oleh: Beixu Li, Xing Ye, Junyi Lin, Kaijun Ma, Meng He, Youxin Fang

Format: Article
Diterbitkan: Elsevier 2024-06-01

Deskripsi

Human induced pluripotent stem cells (iPSCs) have good multi-lineage differentiation potential, which is an ideal model for studying the pathogenesis of diseases and drug screening.Here, we generated an iPSC line, SHUPLi002-A, from peripheral blood mononuclear cells (PBMCs) of a healthy 28-year-old female individual using episomal vectors. SHUPLi002-A is characterized by expression of classical pluripotent stem cell markers as well as teratoma formation assays to evaluate their differentiation capacity in vivo.