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Solvent-free 1,6-conjugate arylation of para-quinone methides: A greener approach to unsymmetrical triarylmethanes
oleh: Yu Hu, Min Tang, Jia-Xuan Chen, Shi-Qian Wei, Yi Tian, Liang-Dong Zhang, Zhang-Qin Liu
Format: | Article |
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Diterbitkan: | Elsevier 2021-09-01 |
Deskripsi
A highly efficient arylation of para-quinone methides (p-QMs) with N,N-dimethylaniline under solvent free condition has been developed, which proceeded via a para-toluenesulfonic acid (TsOH)-promoted 1,6-conjugated addition pathway. This methodology provided a green and sustainable methodology to construct various novel unsymmetrical triarylmethanes (TAMs) with the advantages of good functional group tolerance, scalability, and regioselectivity.