B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV
oleh: Jacopo Polvere, Massimiliano Fabbiani, Gabiria Pastore, Ilaria Rancan, Barbara Rossetti, Miriam Durante, Sara Zirpoli, Enrico Morelli, Elena Pettini, Simone Lucchesi, Fabio Fiorino, Mario Tumbarello, Annalisa Ciabattini, Francesca Montagnani, Donata Medaglini
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
Polvere et al. investigate B cell responses after SARS-CoV-2 vaccination in people living with HIV undergoing anti-retroviral therapy. Spike-specific humoral and B cell responses persist for at least six months although a reduced ACE2/RBD binding inhibition capacity and different memory B phenotypes are observed compared to healthy controls.