Transfusion-dependent anemia, and cytopenia secondary to parvovirus B19 infection as the first manifestation of X-linked hyper immunoglobulin M immunodeficiency syndrome in two male patients in their third decade of life
oleh: Hadel El-Haddad, Eman Ahmed Khan, Ihab El-Hemaidi, Ahmed Absi
| Format: | Article |
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| Diterbitkan: | Wolters Kluwer Medknow Publications 2022-01-01 |
Deskripsi
We describe two male patients with unique mutation of the CD40L gene, unlike the classic presentation of X-linked hyper immunoglobulin M immunodeficiency syndrome (XHIGM syndrome), both were healthy until presenting in their early twenties with a challenging symptomatic transfusion-dependent anemia, investigations confirmed XHIGM syndrome with concurrent chronic parvovirus infection.