Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation
per: Carmen A. Buttler, Nairi Pezeshkian, Melissa V. Fernandez, Jesse Aaron, Sofya Norman, Eric O. Freed, Schuyler B. van Engelenburg
| Format: | Article |
|---|---|
| Publicat: | Nature Portfolio 2018-05-01 |
Descripció
HIV particles contain a relatively low amount of viral envelope (Env), but underlying packaging mechanisms are poorly understood. Here, the authors use superresolution microscopy and show that Env distribution is biased toward the necks of cell-associated particles during assembly.