Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S
oleh: Beatriz Trastoy, Erik Klontz, Jared Orwenyo, Alberto Marina, Lai-Xi Wang, Eric J. Sundberg, Marcelo E. Guerin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-05-01 |
Deskripsi
Endoglycosidase S only recognizes one particular type of glycan within IgG antibodies but the molecular basis for this high specificity is not fully understood. Here, the authors present the crystal structure of product-bound Endoglycosidase S, revealing the determinants for its glycan specificity.