Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
oleh: Chen Zhou, Ling Yan, Wen-hui Zhang, Zhu Liu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-07-01 |
Deskripsi
The VASH2/SVBP heterodimer catalyzes the detyrosination of the α-tubulin C-terminus. Here the authors provide insights into the tubulin detyrosination mechanism by determining the crystal structures of VASH2/SVBP and VASH2/SVBP in complex with a tubulin tail peptide.