Molecular Analysis of Fluoroquinolone-resistant Salmonella Paratyphi A Isolate, India
oleh: Satheesh Nair, Madhulika Unnikrishnan, Keith Turner, Subash Chandra Parija, Carol Churcher, John Wain, Belgode Narasimha Harish
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2006-03-01 |
Deskripsi
Salmonella enterica serovar Paratyphi A is increasingly a cause of enteric fever. Sequence analysis of an Indian isolate showed a unique strain with high-level resistance to ciprofloxacin associated with double mutations in the DNA gyrase subunit gyrA (Ser83→Phe and Asp87→Gly) and a mutation in topoisomerase IV subunit parC (Ser80→Arg).