Cysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM

oleh: S. Rempel, E. Colucci, J. W. de Gier, A. Guskov, D. J. Slotboom

Format: Article
Diterbitkan: Nature Portfolio 2018-08-01

Deskripsi

Uptake of vitamin B12 is essential for many prokaryotes, but in most cases the membrane proteins involved are yet to be identified. Here, the authors use X-ray crystallography and spectroscopy to characterize BtuM, a predicted bacterial substrate-modifying vitamin B12 transporter.