Decarboxylative oxidation-enabled consecutive C-C bond cleavage

oleh: Ruining Li, Ya Dong, Shah Nawaz Khan, Muhammad Kashif Zaman, Junliang Zhou, Pannan Miao, Lifu Hu, Zhankui Sun

Format: Article
Diterbitkan: Nature Portfolio 2022-11-01

Deskripsi

The selective cleavage of inert C(sp3)-C(sp3) bonds and their subsequent functionalization is an important goal in synthetic organic chemistry. Here, the authors developed consecutive C–C bond cleavage from stable trisubstituted acids via photocatalysis and copper catalysis.