TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage
oleh: Nam Soo Lee, Hee Jin Chung, Hyoung-June Kim, Seo Yun Lee, Jae-Hoon Ji, Yoojeong Seo, Seung Hun Han, Minji Choi, Miyong Yun, Seok-Geun Lee, Kyungjae Myung, Yonghwan Kim, Ho Chul Kang, Hongtae Kim
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-01-01 |
Deskripsi
Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.