Multiscale characterization reveals oligomerization dependent phase separation of primer-independent RNA polymerase nsp8 from SARS-CoV-2

oleh: Jinxin Xu, Xin Jiang, Yulong Zhang, Yan Dong, Changli Ma, Hanqiu Jiang, Taisen Zuo, Rui Chen, Yubin Ke, He Cheng, Howard Wang, Jinsong Liu

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

The phase separation behaviour of non-structure protein nsp8 of SARS CoV2 in the primer synthesis mechanism is presented, underpinning the replication of coronavirus.