Ensemble and single-molecule dynamics of IFT dynein in Caenorhabditis elegans cilia
oleh: Jona Mijalkovic, Bram Prevo, Felix Oswald, Pierre Mangeol, Erwin J. G. Peterman
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-02-01 |
Deskripsi
Cytoplasmic dynein 2 drives retrograde intraflagellar transport but little is known about its dynamics. Here the authors use fluorescence microscopy to track labelled dynein 2 inC. elegansat the single-molecule level and report diffusion at the ciliary base, and pausing and directional switches along the cilium.