Gq neuromodulation of BLA parvalbumin interneurons induces burst firing and mediates fear-associated network and behavioral state transition in mice

oleh: Xin Fu, Eric Teboul, Grant L. Weiss, Pantelis Antonoudiou, Chandrashekhar D. Borkar, Jonathan P. Fadok, Jamie Maguire, Jeffrey G. Tasker

Format: Article
Diterbitkan: Nature Portfolio 2022-03-01

Deskripsi

The authors study mechanisms underlying neuromodulatory control of transitions between brain and behavioral states. They identify a mechanism whereby modulation of Gq activity in basolateral amygdala parvalbumin interneurons mediates the transition to a fear-associated network and behavioral state.