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Structural basis of template strand deoxyuridine promoter recognition by a viral RNA polymerase
oleh: Alec Fraser, Maria L. Sokolova, Arina V. Drobysheva, Julia V. Gordeeva, Sergei Borukhov, John Jumper, Konstantin V. Severinov, Petr G. Leiman
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-06-01 |
Deskripsi
Promoter recognition is a critical step in the initiation of transcription of DNA to RNA. Here, the authors describe a novel mechanism by which a phage-encoded RNA polymerase recognizes viral promoters containing deoxyuridines instead of thymidines.