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Quasi-continuous production of highly hyperpolarized carbon-13 contrast agents every 15 seconds within an MRI system
oleh: Andreas B. Schmidt, Mirko Zimmermann, Stephan Berner, Henri de Maissin, Christoph A. Müller, Vladislav Ivantaev, Jürgen Hennig, Dominik v. Elverfeldt, Jan-Bernd Hövener
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-02-01 |
Deskripsi
Magnetic resonance imaging of hyperpolarized contrast agents has enabled unprecedented imaging capabilities in a biomedical setting, but its widespread application is hindered by the time and costs associated with preparing hyperpolarized carbon-13 samples. Here, the authors demonstrate virtually-continuous production of batches of highly-hyperpolarized carbon-13 contrast agents every 15 s within an MRI system without a stand-alone polarizer.