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Successive remodeling of IgG glycans using a solid-phase enzymatic platform
oleh: Yen-Pang Hsu, Deeptak Verma, Shuwen Sun, Caroline McGregor, Ian Mangion, Benjamin F. Mann
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-04-01 |
Deskripsi
A solid-phase glycan remodeling (SPGR) platform is presented. Over thirty enzymes were evaluated for successive glycoengineering of immobilized antibodies with outstanding performance in several SPGR reactions.