Successive remodeling of IgG glycans using a solid-phase enzymatic platform

oleh: Yen-Pang Hsu, Deeptak Verma, Shuwen Sun, Caroline McGregor, Ian Mangion, Benjamin F. Mann

Format: Article
Diterbitkan: Nature Portfolio 2022-04-01

Deskripsi

A solid-phase glycan remodeling (SPGR) platform is presented. Over thirty enzymes were evaluated for successive glycoengineering of immobilized antibodies with outstanding performance in several SPGR reactions.