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<b>Purpose:</b> To evaluate the measure of intraocular pressure (IOP) in patients with scarred corneas obtained from the affected and non-affected areas. <b> Materials and Methods: </b> Eighteen patients with small maculo-leucomatous corneal opacity following microbial keratitis were prospectively included in the study. Goldmann applanation tonometry was done first on the non-affected corneal surface. ProTon tonometry (PT) was then carried out on the same eye, to obtain IOP measurements from the non-affected (PT1) and the affected area (PT2) of the cornea. The IOP measurements were compared using a two-tail paired t test. <b> Results: </b> The mean of IOP measurements of PT 2 and PT1 was 22 mm of Hg (SD &#x00B1; 5.2) and 14.8 mm of Hg (SD &#x00B1; 5.4), respectively. The higher reading of PT2 was statistically significant (<i> P</i> < 0.001). The mean Goldmann applanation tonometry was 14.6 mm of Hg (SD 5.4) and it did not differ significantly (<i> P</i> = 0.86) from the PT1 readings of 14.8 mm of Hg (SD 5.4). <b> Conclusion:</b> In patients with maculo-leucomatous corneal opacity, determination of IOP by ProTon tonometer varies from the affected to the non-affected area. The ProTon tonometer overestimates the level of IOP when it is applied to a leucomatous corneal opacity.