Multistep orthophosphate release tunes actomyosin energy transduction

oleh: Luisa Moretto, Marko Ušaj, Oleg Matusovsky, Dilson E. Rassier, Ran Friedman, Alf Månsson

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Release of the ATP hydrolysis product orthophosphate (Pi) from the myosin active site is central in force generation but is poorly understood. Here, Moretto et al. present evidence for multistep Pi-release reconciling apparently contradictory results.