Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelii var. conescens

oleh: VELE TESEVIC, SLOBODAN MILOSAVLJEVIC, MARINA SOKOVIC, PEDJA JANACKOVIC, SNEZANA TRIFUNOVIC, VLATKA VAJS

Format: Article
Diterbitkan: Serbian Chemical Society 2004-11-01

Deskripsi

Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC.) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi. The overall activity of one of them, 2-hydroxy-2,6,10-trimethyl-7,10-epoxydodeca- 3,11-dien-5-on, was comparable to that of the antibiotic bifonazole.