Efficient and selective α-bromination of carbonyl compounds with N-bromosuccinimide under microwave
oleh: Xiao-Yu Guan, Zahra Al-Misba'a, Kuo-Wei Huang
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2015-11-01 |
Deskripsi
A highly efficient method for the synthesis of α-halocarbonyl compounds has been achieved via selective monobromination of aromatic and aliphatic carbonyl compounds with N-bromosuccinimide catalyzed by p-toluenesulfonic acid under microwave irradiation within 30 min.