Identification of relevant genetic alterations in cancer using topological data analysis
oleh: Raúl Rabadán, Yamina Mohamedi, Udi Rubin, Tim Chu, Adam N. Alghalith, Oliver Elliott, Luis Arnés, Santiago Cal, Álvaro J. Obaya, Arnold J. Levine, Pablo G. Cámara
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-07-01 |
Deskripsi
Rare cancer mutations are often missed using recurrence-based statistical approaches, but are usually accompanied by changes in expression. Here the authors leverage this information to uncover several elusive candidate cancer-associated genes using topological data analysis.