Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes

oleh: Toru Suzuki, Maki Asami, Martin Hoffmann, Xin Lu, Miodrag Gužvić, Christoph A. Klein, Anthony C. F. Perry

Format: Article
Diterbitkan: Nature Portfolio 2016-09-01

Deskripsi

It is unclear what regulates gamete reprogramming competence. Here, the authors inject sperm into parthenogenetic embryos, generating viable offspring and show that mouse embryos in the mitotic cell cycle can reprogram sperm for full term development.