NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells

oleh: Susan L. Kloet, Ino D. Karemaker, Lisa van Voorthuijsen, Rik G. H. Lindeboom, Marijke P. Baltissen, Raghu R. Edupuganti, Deepani W. Poramba-Liyanage, Pascal W. T. C. Jansen, Michiel Vermeulen

Format: Article
Diterbitkan: Nature Portfolio 2018-11-01

Deskripsi

The NuRD complex plays an important role in regulating lineage commitment and cell fate during early embryonic development. Here the authors present an integrative analysis of MBD3/NuRD composition and binding in mouse embryonic stem cells and neural progenitor cells, providing a molecular basis for genome-wide NuRD localization