Hepatitis C Treatment Outcomes in Persons With HIV and Decompensated Cirrhosis Using a Collaborative Multidisciplinary HIV-Centered Approach
oleh: Edward R. Cachay MD, Alvaro Mena MD, PhD, Luis Morano MD, Laura Benitez MD, Ivana Maida MD, Carmen DE Mendoza PhD, Lucas Hill PharmD, Francesca Torriani MD, Vincente Soriano MD, PhD, W. C. Mathews MD, MSPH
| Format: | Article |
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| Diterbitkan: | SAGE Publishing 2021-06-01 |
Deskripsi
Fifty-four consecutive persons with HIV co-infected with hepatitis C virus (HCV) and liver decompensation were treated with direct-acting antivirals (DAA). The HCV treatment was delivered using a multidisciplinary HIV-coinfection model of care integrating sub-specialty services in 3 countries. Of those treated, 91% (95% confidence interval, 80.1 to 95.9) achieved sustained viral response, and only one person died during treatment. Our study provides evidence that HIV providers achieve excellent outcomes when treating patients with histories of decompensated liver disease, with characteristics similar to those studied using a multidisciplinary HIV-centered approach.