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A comprehensive map of alternative polyadenylation in African American and European American lung cancer patients
oleh: Adriana Zingone, Sanju Sinha, Michael Ante, Cu Nguyen, Dalia Daujotyte, Elise D. Bowman, Neelam Sinha, Khadijah A. Mitchell, Qingrong Chen, Chunhua Yan, Phillipe Loher, Daoud Meerzaman, Eytan Ruppin, Bríd M. Ryan
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-09-01 |
Deskripsi
Alternative polyadenylation (APA) regulates the length of the 3′UTR of mRNA. Here, the authors describe a method to accurately measure APA in tumours and apply this method to investigate the differences in APA in African American and European American lung cancer samples.