Somatic Trp53 mutations differentially drive breast cancer and evolution of metastases
oleh: Yun Zhang, Shunbin Xiong, Bin Liu, Vinod Pant, Francis Celii, Gilda Chau, Ana C. Elizondo-Fraire, Peirong Yang, Mingjian James You, Adel K. El-Naggar, Nicholas E. Navin, Guillermina Lozano
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-09-01 |
Deskripsi
Mutations in TP53 gene are very common in cancer development. Here the authors take advantage of murine models to show that somatic Trp53 mutations differentially drive breast cancer and evolution of metastases.