Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation
oleh: Pan-ling Xu, Chien-shan Cheng, Ting Wang, Shu Dong, Ping Li
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2023-02-01 |
Deskripsi
Highlights M0 macrophages accounted for more than 9.8%, indicating a poor prognosis in pancreatic cancer. M0 macrophages proportion were negatively correlated with CD8 + T cells, and immune scores. M0 macrophages promote pancreatic cancer growth in vivo. Elimination of M0 macrophages may be a promising strategy against PAAD.