Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing

oleh: George R. R. Bell, Esther Rincón, Emel Akdoğan, Sean R. Collins

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.