Clinical profile of patients with cardiac amyloidosis in India

oleh: Bishav Mohan, Suvir Singh, Rohit Tandon, Akash Batta, Gautam Singal, Gurbhej Singh, Bhupinder Singh, Abhishek Goyal, Shibba Takkar Chhabra, Khizar Naved, Aayush Jain, Gurpreet S. Wander

Format: Article
Diterbitkan: Elsevier 2023-01-01

Deskripsi

Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had confirmed AL amyloidosis. At the end of the follow up period, 46% patients died, with 30% of the overall cohort dead within six months. Among the survivors, 71% continue to have NYHA grade III/IV symptoms. A suggested algorithm for earlier diagnosis in resource constrained settings is also presented.