Structural analysis of human CEACAM1 oligomerization

oleh: Amit K. Gandhi, Zhen-Yu J. Sun, Yu-Hwa Huang, Walter M. Kim, Chao Yang, Gregory A. Petsko, Nicole Beauchemin, Richard S. Blumberg

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

The crystal structure of human CEACAM1 IgV oligomer and structural analyses provide insight into higher-order oligomerization involving GFCC’ face-mediated homodimerization, flexible ABED interfaces, and dynamic metal-ion bridging.