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Considering the limitation of COVID-19 so that undergraduates can't return to the campus to continue classroom learning, on-line teaching based on Zoom Meetings mixed with rain classroom is being adopted to teach medical immunology and microbiology in students majoring in Chinese Medicine. At the same time, flipped classroom is also applied to this on-line teaching. In this article, it is described in detail how this blending teaching is constructed. What's more, personal teaching reflection and summary is also analyzed.