Investigation of FDG-PET/CT imaging to guide biopsies in the detection of histological transformation of indolent lymphoma
oleh: Caroline Bodet-Milin, Françoise Kraeber-Bodéré, Philippe Moreau, Loïc Campion, Benoît Dupas, Steven Le Gouill
| Format: | Article |
|---|---|
| Diterbitkan: | Ferrata Storti Foundation 2008-03-01 |
Deskripsi
Positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) has been successfully evaluated in the management of non-Hodgkin’s lymphoma (NHL).1–3 Histological transformation (HT) of indolent lymphoma is a dramatic event that occurs in 5–10% of the patients and carries a dismal prognosis.4,5 Previous studies prove that indolent lymphoma entities show a lower FDG uptake when compared with aggressive lymphomas.6–8 We therefore postulated that FDG-PET/CT identifies aggressive transformation sites and can guide biopsies.