Identification of distinct functional thymic programming of fetal and pediatric human γδ thymocytes via single-cell analysis
oleh: Guillem Sanchez Sanchez, Maria Papadopoulou, Abdulkader Azouz, Yohannes Tafesse, Archita Mishra, Jerry K. Y. Chan, Yiping Fan, Isoline Verdebout, Silvana Porco, Frédérick Libert, Florent Ginhoux, Bart Vandekerckhove, Stanislas Goriely, David Vermijlen
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Knowledge about the ontogeny of T cells in the thymus relies heavily on mouse studies because of difficulty to obtain human material. Here the authors perform a single cell analysis of thymocytes from human fetal and paediatric thymic samples to characterise the development of human γδ T cells in the thymus.