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We report the case of a 47-year-old man that was admitted to our hospital secondary to a penetrating brain injury with 2 nails as an attempt of suicide. Emergency head CT scan revealed the presence of 2 nails intracranially. The patient underwent surgical removal of the nails by minimal craniectomy. The particularity of the case is the minimal invasiveness of the approach completed by specific follow-up imagistic studies to maximise the outcome.