POLYMORPHISM OF CHRONIC GLOMERULONEPHRITIS ASSOCIATION WITH ADPRT1 GENE VAL762ALA

oleh: E. S. Kamyshova, M. Yu. Shvetsov, A. E. Shestakov, I. M. Kutyrina, V. V. Nosikov

Format: Article
Diterbitkan: MONIKI 2016-02-01

Deskripsi

Association of polymorphic ADPRT1 gene Val762Ala marker, encoding poly(ADP-ribose)polymerase-l, with the development, course and progress of chronic glomerulonephritis was revealed during investigation. The risk of the chronic glomerulonephritis development is higher in patients-carriers of Val-allele and Val/Val-genotype and lower in those with Ala-allele and Ala/Ala-genotype.