Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

oleh: Yoshitaka Matsuo, Takayuki Uchihashi, Toshifumi Inada

Format: Article
Diterbitkan: Nature Portfolio 2023-01-01

Deskripsi

The colliding ribosomes are ubiquitinated by the sensor protein Hel2, leading to noncanonical subunit dissociation by the ribosome associated quality control trigger (RQT) complex. Here the authors reveal the decoding mechanism of the ribosome ubiquitin code by the RQT complex.