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Geophysical mass flows involve particles of different sizes, a property termed polydispersity. The granular column collapse is a simplified experiment for studying transitional granular flows. Our research focuses on the role that polydispersity has on the velocity and runout distance of dry and immersed granular columns, undergoing a numerical and experimental study. Our results highlight that polydispersity does not have a strong effect on the collapse of dry columns. On the contrary, the collapse sequence of immerse granular columns strongly depend on the polydispersity level.