Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system
oleh: Amit Meir, David Chetrit, Luying Liu, Craig R. Roy, Gabriel Waksman
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-02-01 |
Deskripsi
Legionella pneumophila employs the Type 4B secretion system (T4BSS) to translocate more than 300 effector proteins into the host cell during infection. Here the authors present the crystal structure of the DotM soluble domain and give mechanistic insights into the recruitment of Glu-rich motif-containing effectors to the T4BSS.