Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

oleh: Hongzhang Deng, Weijing Yang, Zijian Zhou, Rui Tian, Lisen Lin, Ying Ma, Jibin Song, Xiaoyuan Chen

Format: Article
Diterbitkan: Nature Portfolio 2020-10-01

Deskripsi

Reactive oxygen species in the tumour microenvironment can have an immunosuppressive effect. Here, the authors devise a nanoparticle that anchors to the extracellular matrix within tumours and scavenges reactive oxygen species, resulting in an enhanced immune response within the tumour.